top of page

Updated on 2024/04/09

2024

  1. Lai ZY, Yang CC, Chen PH, Chen WC, Lai TY, Lu GY, Yang CY, Wang KY, Liu WC, Chen YC, Liu LYM* and Chuang YJ*. Syndecan-4 is required for early-stage repair responses during zebrafish heart regeneration. Mol Biol Rep. 2024 Apr 8. Accepted.

  2. Bohns FR, Akhtar R, Chuang YJ, Chen PY, Bone quality in zebrafish vertebrae improves after alendronate administration in a glucocorticoid-induced osteoporosis model. Journal of the Mechanical Behavior of Biomedical Materials. 2024 Mar, 106521, doi: 10.1016/j.jmbbm.2024.106521.

2023

  1. Chang WC, Chen MJ, Hsiao CD, Hu RZ, Huang YS, Chen YF, Yang TH, Tsai GY, Chou CW, Chen RS, Chuang YJ, Liu YW. The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish. PLoS One. 2023 Oct 30;18(10):e0292858. doi: 10.1371/journal.pone.0292858.

  2. Tang YC, Chuang YJ, Chang HH, Juang SH, Yen GC, Chang JY, and Kuo CC. How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy, Journal of Food and Drug Analysis, 2023, Vol. 31: Iss. 3, Article 2.

  3. Hsu CH, Liu HM, Peir JJ, Lia JW, Chen KS, Chen YW, Chuang YJ, Chou FI. Therapeutic Efficacy and Radiobiological Effects of Boric-Acid-Mediated BNCT in an Osteosarcoma-Bearing SD Rat Model. Life 2023 Feb, 13(2), 514; https://doi.org/10.3390/life13020514

  4. Burbelo PD, Olson SW, Keller JM, Joshi M, Schwartz DM, Chuang YJ, Lambeau G, Beck LH and Waldman M. Prediagnostic Appearance of THSD7A Autoantibodies in Membranous Nephropathy. Kidney360. 2023 Feb 01, 4 (2), 217-225. 

2022

  1. Huang CY, Lai ZY, Hsu TJ, Chou FI, Liu HM, Chuang YJ. Boron neutron capture therapy eliminates radioresistant liver cancer cells by targeting DNA damage and repair responses. J Hepatocell Carcinoma. 2022 Dec 31; 9: 1385-1401.

  2. Lai ZY, Li DY, Huang CY, Tung KC, Yang CC, Liu HM, Chou FI, Chuang YJ. Valproic Acid Enhances Radiosensitization via DNA Double-strand Breaks for Boronophenylalanine-mediated Neutron Capture Therapy in Melanoma Cells. Anticancer Res. 2022 Jul;42(7):3413-3426. doi: 10.21873/anticanres.15828.

2021

  1. Tang YC, Chang HH, Chen HH, Yao JY, Chen YT, Chuang YJ, Chang JY, Kuo CC. A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells. Journal of Food and Drug Analysis. 2021, Vol.29: Iss.4, Article 7. doi.org/10.38212/2224-6614.3376

  2. Chen YC, Chen YH, Chiu H, Ko YH, Wang RT, Wang WP, Chuang YJ, Huang CC, Lu TT. Cell-Penetrating Delivery of Nitric Oxide by Biocompatible Dinitrosyl Iron Complex and Its Dermato-Physiological Implications. International Journal of Molecular Sciences. 2021; 22(18):10101. doi.org/10.3390/ijms22181010

  3. Shyu YM, Liu LYM, Chuang YJ. Synergistic Effect of Simultaneous versus Sequential Combined Treatment of Histone Deacetylase Inhibitor Valproic Acid with Etoposide on Melanoma Cells. J. Mol. Sci. 2021, 22, 10029. https://doi.org/10.3390/ijms221810029

  4. Lai ZY, Tsai KY, Chang SJ, Chuang YJ. Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor. Int. J. Mol. Sci. 2021, 22, 8784. https://doi.org/10.3390/ijms22168784

  5. Tang YC, Hsiao JR, Jiang SS, Chang JY, Chu PY, Liu KJ, Fang HL, Lin LM, Chen HH, Huang YW, Chen YT, Tsai FY, Lin SH, Chuang YJ, Kuo CC. c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation. Theranostics 2021; doi:10.7150/thno.53417

  6. Chang S, Chen JY, Chen BS, Chuang YJ. Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications  Int. J. Mol. Sci. 2021, 22(1), 166

  7. Bohn FR, Chih YR, Chuang YJ, Akhtr R, Chen PY. Influence of Prednisolone and Alendronate on the de novo Mineralization of Zebrafish Caudal Fin. JBMR Plus. 2021, 5 (2), e10435. https://doi.org/10.1002/jbm4.10435

2020

  1. Tang C, Shen C, Zhu K, Zhou Y, Chuang YJ, He C, Zuo Z. Exposure to the AhR agonist cyprodinil impacts the cardiac development and function of zebrafish larvae. Ecotoxicol Environ Saf. 2020 Sep 15;201:110808.

  2. Hung YH, Lin YC, Lin YT, Shih GW, Liao JW, Chen KS, Liu HM, Chen YW, Chuang YJ, Yang CM, Peir JJ, Yang CH, Chou FI. Suitability of boric acid as a boron drug for boron neutron capture therapy for hepatoma. Appl Radiat Isot. 2020 May 30;164:109254

  3. Shih M, Kuo CT, Lin MH, Chuang YJ, Chen H, Yew TR, A 3D-CNT Micro-electrode Array for Zebrafish ECG Study including Directionality Measurement and Drug Test, Biocybernetics and Biomedical Engineering, 2020 March 28 online, Article ref: BBE438; PII: S0208-5216(20)30041-3

  4. Liu LY, Lai ZY, Lin MH, Shih Y, Chuang YJ*. Bioinformatics analysis of hereditary disease gene set to identify key modulators of myocardial remodeling during heart regeneration in zebrafish, EPiC Series in Computing, 2020 Mar, Vol 70. P226-237.

  5. Liu WT, Wu CY, Lu MJ, Chuang YJ, Tsai EM, Leu S, Lin IL, Ko CJ, Chiu CC, Chang WT. The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Oxid Med Cell Longev. 2020 Jan 7;2020:5167292.

2019

  1. Chen KH, Lai ZY, Li DY, Lin YC, Chou FI, Chuang YJ*. Analysis of DNA Damage Responses after Boric Acid-mediated Boron Neutron Capture Therapy in Hepatocellular Carcinoma, Anticancer Research, 2019 Dec;39(12):6661-6671.

  2. Hung YH, Lin YC, Lin YT, Shih GW, Liao JW, Chen KS, Liu HM, Chen YW, Chuang YJ, Yang CM, Peir JJ, Yang CH, Chou FI. Therapeutic Efficacy and Radiobiological Effects of Boric Acid-mediated BNCT in a VX2 Multifocal Liver Tumor-bearing Rabbit Model. Anticancer Res. 2019 Oct;39(10):5495-5504.

  3. Lin YT, Liang SM, Wu YJ, Wu YJ, Lu YJ, Jan YJ, Ko BS, Chuang YJ, Shyue SK, Kuo CC, Liou JY. Cordycepin suppresses endothelial cell proliferation, migration, angiogenesis and tumor growth by regulating focal adhesion kinase and p53, Cancers (Basel). 2019 Feb 1;11(2). pii: E168. 

 

2014~2018

  1. Shen C, Zhou YX, Ruan JP, Chuang YJ, Wnag CG, Zuo ZH. Generation of a Tg(cyp1a-12DRE:EGFP) transgenic zebrafish line as a rapid in vivo model for detecting dioxin-like compounds, Aquat Toxicol. 2018 Dec;205:174-181.

  2. Lin MH, Chou HC, Chen YF, Liu WT, Lee CC,  Liu LY, and Chuang YJ*. Development of a rapid and economic in vivo electrocardiogram platform for cardiovascular drug assay and electrophysiology research in adult zebrafish, Sci Rep. 2018 Oct 30;8(1):15986.

  3. Huang HW, Lin YHm Lin MH, Haung YR, Chou CH, Hong HC, Wang MR, Tseng YT, Lia PC, Chung MC, Ma YJ, Wu SC, Chuang YJ, Wang HD, Wang YM, Huang HD, Lu TT, Liaw WF, Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes, Journal of Biological Inorganic Chemistry, 2018, (ePUb on line 2018/06/04) DOI: 10.1007/s00775-018-1569-

  4. Chang Z, Chen PY, Chuang YJ, Akhtar R. Zebrafish as a model to study bone maturation: nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column, Journal of the Mechanical Behavior of Biomedical Materials, 2018 May 3;84:54-63.

  5. Chang SJ, Liao EC, Yeo HY, Kuo WH, Chen HY, Tsai YT, Wei YS, Chen YJ, Wang YS, Li JM, Shih CC, Chan CH, Lai ZY, Chou HC, Chuang YJ* and Chan HL*. Proteomic Investigating the Cooperative Lethal Effect of EGFR and MDM2 Inhibitors on Ovarian Carcinoma. Archives of Biochemistry and Biophysics, 2018 (E-pub on 12 April 2018; https://doi.org/10.1016/j.abb.2018.04.004)

  6. Liu FY, Hsu TC, Choong P, Lin MH, Chuang YJ, Chen BS, Lin C. Uncovering the regeneration strategies of zebrafish organs: a comprehensive systems biology study on heart, cerebellum, fin, and retina regeneration. BMC Syst Biol. 2018 Mar 19;12(Suppl 2):29.

  7. Wang TZ, Chang KC, Chen LH, Liao SY, Yeh CW, Chuang YJ. Effects of an injectable functionalized self-assembling
    nanopeptide hydrogel on angiogenesis and neurogenesis for regeneration of the central nervous system. Nanoscale, 2017,9, 16281-16292

  8. Bai YC, Hsia YC, Lin YT, Chen KH, Chou FI, Yang CM, Chuang YJ*. Effect of tumor conditions on selective uptake of boric acid in human hepatoma HepG2 cells. Anticancer Res. 2017 Nov;37(11):6347-6353

  9. Yang CH, Yeh YJ, Wang JY, Liu YW, Chen YL, Cheng HW, Cheng CM, Chuang YJ, Yuh CH, Chen YR. NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish. Sci Rep. 2017 Jul 12;7(1):5241.2017 

  10. Wu HC, Lyau JB; Lin MH, Chuang YJ, Chen H.  Multilayer Microfluidic Systems with Indium-Tin-Oxide Microelectrodes for Studying Biological Cells. Journal of Micromechanics and Microengineering. 2017 June; 27:075013 (15pp)

  11. Lai ZY, Yeo HY, Chen YT, Chang KM, Chen TC, Chuang YJ*, Chang SJ. PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line. Oncotarget. 2017 Jul 11;8(28):45323-45334.

  12. Lee IJ, Yang YC, Hsu JW, Chang WT, Chuang YJ, Liau I. Zebrafish model of photochemical thrombosis for translational research and thrombolytic screening in vivo. J Biophotonics. 2017 Apr;10(4):494-502.

  13. 林旻萱、莊永仁*, 繽紛斑馬魚現形記, 科學人雜誌, 180期 2017年2月

  14. Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ*. Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. J Biomed Sci. 2016 Aug 2;23(1):59.

  15. You MS, Jiang YJ, Yuh CH, Wang CM, Tang CH, Chuang YJ, Lin BH, Wu JL, Hwang SP. A Sketch of the Taiwan Zebrafish Core Facility. Zebrafish. 2016 Jul;13 Suppl 1:S24-9. doi: 10.1089/zeb.2015.1208.

  16. Pan AI, Lin MH, Chung HW, Chen H, Yeh SR, Chuang YJ, Chang YC, Yew TR. Direct-growth carbon nanotubes on 3D structural microelectrodes for electrophysiological recordings. Analyst. 2016 Jan 7;141(1):279-84.

  17. Chen CJ, Tsai KC, Kuo PH, Chang PL, Wang WC, Chuang YJ, Chang MDT. A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition. BioMed Research International. 2015 Volume 2015 (2015), Article ID 237969.

  18. Lin C, Lin CN, Wang YC, Liu FY, Chien YW, Chuang YJ, Lan CY, Hsieh WP, Chen BS. Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection. BMC Syst Biol. 2014 Dec 12;8 Suppl 5:S6.

  19. Lin C, Lin CN, Wang YC, Liu FY, Chuang YJ, Lan CY, Hsieh WP, Chen BS. The role of TGF-ß signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach. BMC Syst Biol. 2014 Oct 24;8(1):116.

  20. Wu CC, Tsai TH, Chang C, Lee TT, Lin C, Cheng IH, Sun MC, Chuang YJ, Chen BS. On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 2014 Jun 13;9(6):e97902.

  21. Wang YC, Tsai IC, Lin C, Hsieh WP, Lan CY, Chuang YJ, Chen BS. Essential Functional Modules for Pathogenic and Defensive Mechanisms in Candida albicans Infections. Biomed Research International. 2014; 2014:136130. Article ID136130

  22. Lin LH, Chang SJ, Hu RY, Lin MW, Lin ST, Huang SH, Lyu PC, Chou HC, Lai ZY, Chuang YJ* and Chan HL*. Biomarker Discovery for Neuroendocrine Cervical Cancer. Electrophoresis. 2014 Jul;35(14):2039-45.

 

2009~2013

  1. Lin CC, Chang TC, Lai CH, Chien CW, Liang CF, Adak AK, Chuang YJ, Chen YJ. Synthesis and Evaluation of a Photoactive Probe with a Multivalent Carbohydrate for Capturing Carbohydrate-Lectin Interactions. Bioconjug Chem. 2013 Nov 20;24(11):1895-906.

  2. Chen YY, Chao CC, Lui FC, Hsu PC, Chen HF, Peng CH, Chuang YJ, Hsieh WP, Wang DS. Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction study. PLoS One. 2013 Sep 3;8(9):e72483.

  3. Lai CH, Chang TC, Chuang YJ, Tzou DL, Lin CC. Stepwise Orthogonal Click Chemistry toward Fabrication of Paclitaxel/Galactose Functionalized Fluorescent Nanoparticles for HepG2 cell Targeting and Delivery. Bioconjug Chem. 2013 Oct 16;24(10):1698-709.

  4. Chen CH, Ho YC, Ho HH, Chang IC, Kirsch KH, Chuang YJ, Layne MD, Yet SF. Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration. Cardiovasc Res. 2013 Dec 1;100(3):461-71.

  5. Lai CH, Lai NC, Chuang YJ, Chou FI, Yang CM, Lin CC. Trivalent galactosyl-functionalized mesoporous silica nanoparticles as a target-specific delivery system for boron neutron capture therapy. Nanoscale. 2013 Oct 7;5(19):9412-8.

  6. Wang YC, Lin C, Chuang MT, Hsieh WP, Lan CY, Chuang YJ, Chen BS. Interspecies protein-protein interaction network construction for characterization of host-pathogen interactions: a Candida albicans-zebrafish interaction study. BMC Syst Biol. 2013 Aug 16;7:79. doi: 10.1186/1752-0509-7-79.

  7. Yeh CT, Su CL, Huang CY, Lin JK, Lee WH, Chang PM, Kuo YL, Liu YW, Wang LS, Wu CH, Shieh YS, Jan YH, Chuang YJ, Hsiao M, Wu AT. A preclinical evaluation of antimycin a as a potential anti-lung cancer stem cell agent. Evid Based Complement Alternat Med. 2013; 2013:910451.

  8. Chen MH, Jan YH, Chang PM, Chuang YJ, Yeh YC, Lei HJ, Hsiao M, Huang SF, Huang CY, Chau GY. Expression of GOLM1 Correlates with Prognosis in Human Hepatocellular Carcinoma. Ann Surg Oncol. 2013 Dec;20 Suppl 3:S616-24.

  9. Huang WC, Yang CC, Chen IH, Liu YM, Chang SJ, Chuang YJ*. Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish. PLoS One. 2013 Jun 21;8(6):e66613.

  10. Hsu PC, Chao CC, Yang CY, Ye YL, Liu FC, Chuang YJ, Lan CY. Diverse Hap43-independent functions of the Candida albicans CCAAT-binding complex. Eukaryot Cell. 2013 Jun;12(6):804-15.

  11. Kuo ZY, Chuang YJ, Chao CC, Liu FC, Lan CY and Chen BS. Identification of infection-related and defense-related genes via a dynamic host-pathogen interaction network using a C. Albicans - zebrafish infection model. Journal of Innate Immunity, 2013 ;5(2):137-52.

  12. Chen IH, Wang HH, Hsieh YS, Yeh HI, Chuang YJ*. PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish. Cardiovascular Research, 2013 Mar 1;97(3):443-53.

  13. Jan YH, Tsai HY, Yang CJ, Huang MS, Yang YF, Lai TC, Lee CH, Jeng YM, Huang CY, Su JL, Chuang YJ, Hsiao M. Adenylate kinase 4 promotes lung cancer metastasis through the downregulation of ATF3 and correlates with poor clinical outcome. Cancer Res, 2012, Oct 1;72(19):5119-29.

  14. Yeh YT, Lee CI, Lim SH, Chen LJ, Wang WL, Chuang YJ, Chiu JJ. Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc. Biomaterials. 2012 Oct;33(28):6728-38.

  15. Chan HS, Chang SJ, Wang TY, Ko HJ, Lin YC, Lin KT, Chang KM, Chuang YJ*. Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells. PLoS One. 2012;7(1):e30397.

  16. Chen FF, Lin WH, Lin SC, Kuo JH, Chu HY, Huang WC, Chuang YJ, Lee SC, Sue SC. Significance of heparin binding to basic residues in homologous to amino terminus domain of hepatoma-derived growth factor and related proteins. Glycobiology. 2012 May;22(5):649-61.

  17. Lai CH, Lin YC, Chou FI, Liang CF, Lin EW, Chuang YJ, Lin CC. Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy. Chem Commun (Camb). 2012 Jan 14;48(4):612-4.

  18. Kuo MW, Wang CH, Wu HC, Chang SJ, Chuang YJ*. Soluble THSD7A Is an N-Glycoprotein That Promotes Endothelial Cell Migration and Tube Formation in Angiogenesis. PLoS One. 2011;6(12):e29000.

  19. Peng CH, Liao CT, Peng SC, Chen YJ, Cheng AJ, Juang JL, Tsai CY, Chen TC, Chuang YJ, Tang CY, Hsieh WP, Yen TC. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS One. 2011;6(8):e23452.

  20. Chen BS, Lin YP, Chuang YJ. Robust H-infinity Observer-based Tracking Control of Stochastic Immune Systems under Environmental Disturbances and Measurement Noises. Asian J Control. 2011; 13(5):667-690, September 2011. DOI: 10.1002/asjc.421

  21. Luo WY, Shih YS, Lo WH, Chen HR, Wang SC, Wang CH, Chien CH, Chiang CS, Chuang YJ, Hu YC. Baculovirus vectors for antiangiogenesis-based cancer gene therapy. Cancer Gene Ther. 2011 Jun 24. doi: 10.1038/cgt.2011.35.

  22. Chen BS, Chang CH, Chuang YJ. Robust control of immune systems under noises: stochastic game approach. Handbook of Statistical Bioinformatics. Springer Handbooks of Computational Statistics, 2011, Part 3, 601-627, DOI: 10.1007/ ISBN: 978-3-642-16344-9

  23. Wang CH, Chen IH, Kuo MW, Su PT, Lai ZY, Wang CH, Huang WC, Hoffman J, Kuo CJ, You MS, Chuang YJ*. Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development. Dev Dyn. 2011 Jun; 240(6):1412-21. doi: 10.1002/dvdy.22641.

  24. Kang CC, Chuang YJ, Tung KC, Cho CC, Tang CY, Peng SC, Wong DS. A Genetic Algorithm-based Boolean Delay Model of Intracellular Signal Transduction in Inflammation. BMC Bioinformatics. 2011, 12(Suppl 1):S17

  25. Lin RZ, Wang TP, Hung RJ, Chuang YJ, Chien CC, Chang HY. Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species. J Cell Physiol. 2011 Jul;226(7):1750-62.

  26. 黃威彰、童凱澤、莊永仁, 透視斑馬魚, 科學人雜誌, 109期 2011年3月

  27. Lai CH, Lin CY, Wu HT, Chan HS, Chuang YJ, Chen CY, Lin CC. Galactose Encapsulated Multifunctional Nanoparticle for HepG2 Cell Internalization. Advanced Functional Materials. 2010. 20(22):3948-3958, doi:10.1002 / adfm. 201000461

  28. Huang WC, Hsieh YS, Chen IH, Wang CH, Chang HW, Yang CC, Ku TH, Yeh SR, Chuang YJ*. Combined Use of MS-222 (Tricaine) and Isoflurane Extends Anesthesia Time and Minimizes Cardiac Rhythm Side Effects in Adult Zebrafish. Zebrafish. 2010 Sep;7(3):297-304.

  29. Peng SC, Wong DS, Tung KC, Chen YY, Chao CC, Peng CH, Chuang YJ*, Tang CY. Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappaB signaling-induced gene expression responses in inflammation. BMC Bioinformatics. 2010 Jun 8;11:308.

  30. Chao CC, Hsu PC, Jen CF, Chen IH, Wang CH, Chan HC, Tsai PW, Tung KC, Wang CH, Lan CY, Chuang YJ*. Zebrafish as a model host for Candida albicans infection. Infect Immun. 2010 Jun;78(6):2512-21. Epub 2010 Mar 22.

  31. Yang SK, Wang YC, Chao CC, Chuang YJ, Lan CY, Chen BS. Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses. BMC Med Genomics. 2010 May 24;3:19.

  32. Wang CH, Su PT, Du XY, Kuo MW, Lin CY, Yang CC, Chan HS, Chang SJ, Kuo C, Seo K, Leung LL, Chuang YJ*. Thrombospondin type I domain containing 7A (THSD7A) mediates endothelial cell migration and tube formation. J Cell Physiol. 2010 Mar; 222(3):685-94.

  33. Chen GY, Shiah HC, Su HJ, Chen CY, Chuang YJ, Lo WH, Huang JL, Chuang CK, Hwang SM, Hu YC. Baculovirus transduction of mesenchymal stem cells triggers the toll-like receptor 3 pathway. J Virol. 2009 Oct;83(20):10548-56

 

2004~2008

  1. Chen BS, Yang SK, Lan CY, Chuang YJ. A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining. BMC Med Genomics. 2008Sep 30;1:46.

  2. Chen BS, Chang CH, Chuang YJ. Robust model matching control of immune systems under environmental disturbances: dynamic game approach. J Theor Biol. 2008 Aug 21;253(4):824-37. Epub 2008 Apr 29.

  3. Chen ML, Adak AK, Yeh NC, Yang WB, Chuang YJ, Wong CH, Hwang KC, Hwu JR, Hsieh SL, Lin CC. Fabrication of an oriented Fc-fused lectin microarray through boronate formation. Angew Chem Int Ed Engl. 2008;47(45):8627-30.

  4. Zhang W,Chuang YJ, Jin T, Swanson R, Xiong Y, Leung L, Olson ST. Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells. Cancer Res. 2006 May 15;66(10):5047-55.

  5. Zhang W,Chuang YJ, Swanson R, Li J, Seo K, Leung L, Lau LF, Olson ST. Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells. Blood. 2004 Feb 15;103(4):1185-91.

 

Before 2003

  1. Bedsted T, Swanson R, Chuang YJ, Bock PE, Björk I, Olson ST. Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites. Biochemistry. 2003 Jul 15;42(27):8143-52.

  2. Olson ST, Chuang YJ. Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases. Trends Cardiovasc Med. 2002 Nov;12(8):331-8. Review.

  3. Chuang YJ, Swanson R, Raja SM, Bock SC, Olson ST. The antithrombin P1 residue is important for target proteinase specificity but not for heparin activation of the serpin. Characterization of P1 antithrombin variants with altered proteinase specificity but normal heparin activation. Biochemistry. 2001 Jun 5;40(22):6670-9.

  4. Chuang YJ, Swanson R, Raja SM, Olson ST. Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin. J Biol Chem. 2001 May 4;276(18):14961-71.

  5. Chuang YJ, Gettins PG, Olson ST. Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --> Pro mutation. J Biol Chem. 1999 Oct 1;274(40):28142-9.

bottom of page